Osmosis Calm Gentle Retinal Serum

4.40 out of 5
(5 customer reviews)


Osmosis Calm is designed for moderately-sensitive skin types who desire a dramatic restoration of the skin rejuvenation process. The Osmosis Vitamin A serums are the most powerful age-reversing serums available. It encourages the skin to calm inflammation, restore the protective barrier, increase skin nutrients and immune repair, rebuild the thin dermis, normalise oil, hydrate, firm and protect skin from UV rays.

Osmosis is transitioning to NEW packaging. During this time you may receive the new or old packaging according to stock levels.

Purchase this product now and earn 162 Points!

Add to Wishlist
Add to Wishlist
no nasties skin care
plant based skin care
medical strength skin care
clinically formulated skin care
cruelty free skin care
official stockist

Osmosis Calm is an all-natural product, which has been specially designed to rejuvenate and restore damaged or dull skin. It is best for people with moderately-sensitive skin. This product is an Osmosis’ entry level vitamin A serum, however it certainly offers the best age-reversing solution of any serum currently on the market.

Osmosis Calm helps to control and reduce inflammation and also restore protective lipid barriers. By increasing the nutrient levels in your skin, it boosts immune repair.

Further benefits include its hydrating properties and the ability to normalise oil production, ultimately helping to rebuild the thin dermis layer and develop firm, healthy skin that is protected from harmful UV rays.

A key ingredient in the makeup of Osmosis Calm is Sea Buckthorn oil. This fusion of more than 20 vitamins also provides bioactive compounds and antioxidants that deliver a powerful punch for your skin.

Also, it includes Phosphatidylcholine, which is a water-binding agent. This allows Osmosis Calm to penetrate the skin and absorb well, without feeling greasy on your skin.

If you’ve never used a Vitamin A before, or have sensitive or reactive skin, and want to change it, then this is the product for you.

Best For

Ageing, sensitive, dry or irritated skin types.

*Please consult your Doctor prior to using a Vitamin A product whilst pregnant or breastfeeding.

Benefits of Osmosis Calm

  • 7 non-irritating collagen and elastin stimulators.
  • Calms inflammation.
  • Increases nutrient supply and moisture.
  • Product size is 30ml.

Osmosis Calm Skin Loving Ingredients

Retinaldehyde* | Vitamin A that works with the skin to promote cellular turn over and helps reduce multiple signs of aging without causing irritation or sun sensitivity. Clinically proven to outperform retinoic acid in long-term collagen production.

Chlorella | Protects and stimulates collagen and elastin, provides antioxidant support, encourages cell detoxification.

Sea Buckthorn | High content of Omega 7 fatty acids, tocopherols, carotenoids, and phytosterols; enhances cell regeneration, promotes healing, is anti-inflammatory, firms and tones sagging skin smoothing out wrinkles. Used to soothe, heal, and promote healthy barrier function in allergic and inflammatory skin.

Wild Cherry Bark | Historically the inner bark of Wild Cherry has been used for its highly anti-inflammatory and astringent properties to treat rashes, psoriasis, and eczema, as it soothes, detoxifies, and stimulates healing.


Osmosis Holistic Approach

We are BIG fans of Osmosis in our clinic. This is because we see GREAT results with our in-clinic clients, as well as ourselves. When we want results, and we want to see them consistently appear, we lean towards this range. With a view to constantly update and improve, you know you’re receiving the latest in technology and research. Ingredients are natural and designed to give your skin the strength it needs to heal and improve. Rather than stripping and over-exfoliating your skin to kick-start renewal, it feeds your skin an abundance of nutrients instead. Proving time and time again that a gentle and strengthening approach provides amazing results.

This brand also believes that reducing inflammation is key to great skin, taking a holistic approach. Providing both internal and external products to ensure your skin can reach and maintain the great results you see. Designed to work together, this range aims to reduce the problem from the source, as well as the “secondary” issues that you see appear on your skin.

Reasons you’ll LOVE Osmosis

  • Clean, non-toxic ingredients free of sodium lauryl sulphate, phthalates,
    parabens, gluten, artificial colours, and fragrances.
  • Doctor-developed and clinically validated.
  • Patented formulas and exclusive ingredients with pharmaceutical-grade delivery systems.
  • Holistic, non-inflammatory approach.
  • Cruelty-Free (Leaping Bunny Approved), vegan and gluten-free.
  • Recyclable Packaging.

Water (Aqua), Glycerin, Phosphatidylcholine, Pentylene Glycol, Asiaticoside, Epilobium Angustifolium Flower/Leaf/Stem Extract, Hippophae Rhamnoides (Sea Buckthorn) Extract, Chlorella Vulgaris Extract, Palmitoyl Tripeptide-38, Chrysanthemum Parthenium (Feverfew) Extract, Niacinamide, Dimethyl Sulfone, Lactic Acid, Panthenol, Pyridoxine HCl, Fulvic Acid, Prunus Serotina (Wild Cherry) Bark Extract, Retinaldehyde (.0375%), Hydroxyproline, Beta-Glucan, Rubus Chamaemorus (Cloud Berry) Seed Oil, Cinnamomum Camphora (Camphor) Bark Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Rosa Damascena Flower Oil, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Hydroxypropyl Cyclodextrin, Cyclodextrin, Alcohol, Xanthan Gum, Sodium Hydroxide, Benzyl Alcohol, Potassium Sorbate.

Shake lightly and apply 1-2 pumps to clean damp skin. Follow with your moisturiser. If this is your first Vitamin A product we suggest you begin using it every 3rd night, slowly increasing to nightly and then morning and night. This may take a few weeks. We always recommend applying sunscreen during the day to protect skin against sunburn and premature ageing.

Please consult your Doctor prior to using a Vitamin A product whilst pregnant or breastfeeding.

5 reviews for Osmosis Calm Gentle Retinal Serum

  1. 3 out of 5

    Anonymous (verified owner)

    I love Osmosis MD products and the Skin Care Clinic had an amazing service, but sadly, this retinol serum is not for me 🙁 It contains rose, which I have overlooked checking the ingredients and it always has my skin react badly (redness mostly). I’ll have to gift this to someone. Overall, the product feels gentle on the skin so could be great for someone with less sensitivity.

  2. 5 out of 5

    Anonymous (verified owner)

    I am an older lady and my skin has become quite sensitive at times particularly in winter..The skin care clinic recommended Osmosis MD CALM Retinol Serum. I have been using this for a few weeks now and I am extremely happy. Only a small amount is needed as it goes a long way. My redness has settled down and sensitivity has improved.

  3. 5 out of 5

    Lauren B. (verified owner)

    I was recommended to use Calm in conjunction with MD rescue after I had just finished breast feeding, after about 2 months of using Calm I could see a massive improvement in my skin and most importantly it restored my skin barrier I would definitely recommend using this product especially if you are a first time user of any Vitamin A Serums.

  4. 5 out of 5

    Anonymous (verified owner)

    I absolutely love this product. It’s the only thing I use in my skin now, it balances the oils on my skin so well that I don’t need any moisturising cream. I just wash my face with water and apply this once a day at night. That’s it. My skin feels soft, smooth and clear. It has also massively reduced hormonal breakouts I have around the chin, I used to get quite a few spots each month, now after 4months of this product I get none to maybe one which goes away quickly. I’m so happy 😉 I had some redness too but I think that was more dun damage than Rosacea but this has reduced a little too. I love this product. Love the fact that I don’t need to put anything else on my skin. We tend to put so much crap on our faces that I sometimes think this is what creates problems in the first place. I started using this product slowly, 2-3 times a week, now I use it once a day at night. I’ve had no irritation or dryness. Just perfectly calm and happy skin. 

  5. 4 out of 5

    Jarrah M. (verified owner)

    I started using this product when I became quite concerned that I had really sensitive skin including redness and dry/flaky skin especially around the nose area. Since starting this product there has been a remarkable improvement which I noticed within a month of using it. I now am a long-time user and have no plans to discontinue use. I now realise that my ‘sensitive skin’ was probably due to the harsh skin care regime I had in place before I tried Osmosis MD. I also use the Osmosis Gentle Cleanser and Quench products which really makes a huge difference to my skin. It feels so hydrated with noticeable implications.

Add a review

Your email address will not be published. Required fields are marked *



Follow us on Instagram